From September 2009 to October 2011, 54 consecutive patients underwent coronary intervention in our institution using a GuideLiner 21 out of 54 coronary applications were motivated by the need to increase support to cross CTOs, predominantly of the RCA. Patient demographics, lesion and vessel characteristics, procedural details and outcomes were prospectively entered into our database and analysed. Methods and results: Consecutive patients undergoing coronary or peripheral interventions where a GuideLiner was used were recruited into this study. We conducted a study on the feasibility and safety of utilising this catheter in a wider array of complex coronary interventions. The GuideLiner is a monorail catheter originally developed to facilitate delivery of stents to target lesions in tortuous vessels. The full list of adopted Test Guidelines, the draft TGs under public commenting rounds, the draft Guidance and review documents are available on the Test Guidelines Programme.Aims: Challenging coronary anatomies including chronic total occlusions (CTO), extreme vessel tortuosity, diseased bypass grafts, and anomalous coronary arteries pose difficulties in coronary interventions. Section 4: Health Effects (Software for TG 455, TG 432,TG 425 and QMRF for TG 497 Excel spreadsheets for TG 458 and TG 442C, Appendix III example of protocol for TG 470).Section 3: Environmental Fate and Behaviour ( Softwares for TG 305 and TG 318).Section 2: Effects on Biotic Systems ( Software for TG 223).Section 1: Physical Chemical Properties.The OECD Guidelines for the Testing of Chemicalsare split into five sections: Under this system, laboratory test results related to the safety of chemicals that are generated in accordance with OECD Test Guidelines and OECD Principles of Good Laboratory Practicesare accepted in all OECD countries and adherent countries for the purpose of safety assessment and other uses relating to the protection of human health and the environment. OECD Test Guidelines are covered by the OECD Mutual Acceptance of Data (MAD) system. The Guidelines are elaborated with the assistance of experts from regulatory agencies, academia, industry, environmental and animal welfare organisations. These Guidelines are continuously expanded and updated to ensure they reflect the state-of-the-art science and techniques to meet member countries regulatory needs. A ccepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals (industrial chemicals, pesticides, personal care products, etc.). ![]() The OECD Guidelines for the Testing of Chemicalsare a unique tool for assessing the potential effects of chemicals on human health and the environment. ![]() Read the full call for financial support here. This is a dynamic space that brings key players together, including small businesses, to consolidate robust approaches to achieve relevant and reliable innovative methods for chemicals testing. The mechanisms and processes in place to facilitate standardisation and validation studies require sustainable and realistic financial support to meet the needs of evolving chemicals regulations. With the aim to accelerate the pace of chemical safety testing and assessment, reduce the use of laboratory animals and to better protect human health and the environment, the Working Party of the National Coordinators to the Test Guidelines Programme (WNT), supported by the OECD Chemicals and Biotechnology Committee, calls for urgent mobilisation of national and regional resources for the demonstration of reproducibility and reliability of methods developed in single laboratories. What's new: the OECD calls for urgent mobilisation of national and regional resources to support the validation of new methods for the safety testing of chemicals Green growth and sustainable development.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |